The Portuguese ambassador will flag off more than 50 classics from London on 27 April en route to Lisbon 2386 miles away.
A broad range of cars is set to tackle the rally’s 39 tests and regularities including a 1930 Austin Seven Ulster and, from the same year, a Riley Brooklands Nine, plus a 1962 Rolls-Royce Silver Cloud and a 1973 Ferrari Dino 246GTS.
Drivers from countries such as the UK, Australia, Hong Kong, Germany, Switzerland, the USA and Mexico will travel more than 200 miles a day before arriving in Lisbon on 5 May.
Organised by the Historic Endurance Rallying Organisation, the event is a qualifying round of the 2013 HERO Cup.
HERO’s joint managing director Patrick Burke said: “The response has been amazing. This will be a real challenge for drivers, but also a moving spectacle for people along the route and we encourage them to come out and watch.”
The event’s schedule is as follows:
• 27 April – Greenwich to Portsmouth (United Kingdom)
• 28 April – St Malo to Poitiers (France)
• 29 April – Poitiers to Pau (France)
• 30 April – Pau to Burgos (Spain)
• 1 May – Burgos to Leon (Spain)
• 2 May – Leon to Ourense (Spain)
• 3 May – Ourense to Vila Real (Portugal)
• 4 May – Vila Real to Caramulo (Portugal)
• 5 May – Caramulo to Lisbon (Portugal)